It's a very Effective ingredient on the skin and is one of the main constituents of traditional calamine lotion which is used extensively to relieve redness stinging and irritation of the skin. Calamine powder gives the skin a gentle toning and antiseptic action. It has soothing properties that act on the skin when applied to give a cooling sensation that distracts from the itching sensation caused by the oil secretions from toxic plants as they come in contact with your skin. Effective on nappy rash and other mild skin problems in infants calamine is a must have for parents during the infancy stage of their children. As infants grow older and before the challenges of adolescent acne the first skin problems they come in contact with is often measles and use of calamine lotion has been a source of constant relief for these issues since ages.