Karela also known as bitter melon and bitter gourd or momordica charantia is especially useful in diabetes as it stimulates pancreas liver and spleen; improves absorption of food and better regulation of blood sugar level. Workings of liver determine a lot about skin health so karela also benefits in skin diseases. It is also beneficial in kidney stone. Karela is also recommended in breast cancer to minimize further spread. Effect on doshas: karela pacifies all the three doshas so it is quite useful in diseases of tridosha origin.