CloSYS fluoride toothpaste delivers a unique combination of powerful ingredients that kill harmful bacteria that cause plaque while it's gentle enough for people with mild to moderate sensitive mouths to use every day. CloSYS is one of the few toothpastes available that does not contain sulfates (foaming agents) which has been linked to allergies mouth ulcers and canker sores. Now you brush away cavities bad breath and tough stains like coffee tea and wine twice a day without irritation.